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Symbol
Name
ID

Spry2
sprouty RTK signaling antagonist 2
MGI:1345138

Phenotype annotations related to cardiovascular system

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Purpura	Hypertension
Disease(s) Associated with SPRY2	Purpura	Hypertension
IgA glomerulonephritis

Mouse Phenotypes		cardiovascular system phenotype	abnormal cardiac epithelial to mesenchymal transition	abnormal cardiac outflow tract development	persistent truncus arteriosus	abnormal heart development	abnormal heart morphology	double outlet right ventricle	atrioventricular septal defect	ventricular septal defect	bicuspid aortic valve
Availability	Mouse Genotype	cardiovascular system phenotype	abnormal cardiac epithelial to mesenchymal transition	abnormal cardiac outflow tract development	persistent truncus arteriosus	abnormal heart development	abnormal heart morphology	double outlet right ventricle	atrioventricular septal defect	ventricular septal defect	bicuspid aortic valve
	Mesp1^tm2(cre)Ysa/Mesp1⁺ Tg(CAG-Bgeo,-Spry2,-ALPP)1Mrt/0 (conditional)
	Pax3^tm1(cre)Joe/Pax3⁺ Tg(CAG-Bgeo,-Spry2,-ALPP)1Mrt/0 (conditional)	*

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/30/2024 MGI 6.23